Rong Tian, PhD
Joint Professor of Anesthesiology and Bioengineering
Adjunct professor, Biochemistry
Director, Mitochondria and Metabolism Center, University of Washington
The Tian Lab is interested in the molecular mechanisms regulating mitochondrial function and cardiac metabolism as well as their roles in the pathogenesis of human diseases.
Honors and awards
2010 – Distinguished Achievement Award, American Heart Association Council on Basic Science
2008 – Election to the American Society of Clinical Investigation
2003-2007 – Established Investigator Award of the American Heart Association
2004 – Young Investigator Award of the American Physiological Society
1999 – Scholars in Medicine at Harvard Medical School
Kim M, Hunter RW, Garcia-Menendez L, Gong G, Yang YY, Kolwicz SC Jr, Xu J, Sakamoto K, Wang W, Tian R. (2014). Mutation in the γ2-subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage. Circulation Research, 114 (6): 966-75.
Karamanlidis G, Lee CF, Garcia-Menendez L, Kolwicz Jr. SC, Suthammarak W, Gong G, Sedensky MM, Morgan PG, Wang W, Tian R. (2013). Mitochondrial Complex I Deficiency increases protein acetylation and accelerates heart failure. Cell Metabolism, 18 (2): 239-50. PMCID: PMC3779647
Kolwicz, Jr SC, Olson DP, Marney LC, Garcia-Menendez L, Synovec RE, Tian R. (2012). Cardiac-specific deletion of acetyl CoA carboxylase 2 (ACC2) prevents metabolic remodeling during pressure-overload hypertrophy. Circ Res, 111 (6): 728-38. PMID: 22730442
Yan J, Young ME, Cui L, Lopaschuk GD, Liao R, Tian R. (2009). Increased glucose uptake and oxidation in mouse hearts prevents high fatty acid oxidation but causes cardiac dysfunction in diet-induced obesity. Circulation, 119: 2818-2828. PMCID: PMC2765220
Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M , Seidman CE, Seidman JG, Ingwall JS ,Balschi JA, and Tian R. (2007). Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest, 117(5):1432-9. PMCID: PMC1847536